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Mevalonate pathway

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Current revision (11:07, 3 October 2022) (edit) (undo)
 
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<StructureSection load='' size='350' side='right' scene='HMG-CoA_Reductase/1dq8_starting_scene/1' caption='Crystal Structure of HMG-CoA, (PDB code [[1dq8]])'>
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<StructureSection load='4c2j' size='350' side='right' caption='Human 3-ketoacyl-CoA complex with CoA and ethylene glycol (PDB code [[4c2j]])' scene='44/447919/Cv/7'>
Production of mevalonate is the rate-limiting and irreversible step in cholesterol synthesis and is the site of action for statins.
Production of mevalonate is the rate-limiting and irreversible step in cholesterol synthesis and is the site of action for statins.

Current revision

Human 3-ketoacyl-CoA complex with CoA and ethylene glycol (PDB code 4c2j)

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Alexander Berchansky

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