1vie

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<StructureSection load='1vie' size='340' side='right'caption='[[1vie]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1vie' size='340' side='right'caption='[[1vie]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1vie]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VIE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1VIE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1vie]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VIE FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SYNTHETIC GENE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vie OCA], [https://pdbe.org/1vie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vie RCSB], [https://www.ebi.ac.uk/pdbsum/1vie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vie ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1vie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vie OCA], [http://pdbe.org/1vie PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vie RCSB], [http://www.ebi.ac.uk/pdbsum/1vie PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vie ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DYR21_ECOLX DYR21_ECOLX]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
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[https://www.uniprot.org/uniprot/DYR21_ECOLX DYR21_ECOLX] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Howell, E E]]
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[[Category: Howell EE]]
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[[Category: Matthews, D A]]
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[[Category: Matthews DA]]
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[[Category: Narayana, N]]
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[[Category: Narayana N]]
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[[Category: Xuong, N H]]
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[[Category: Xuong N-H]]
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[[Category: Methotrexate resistance]]
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[[Category: Nadp]]
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[[Category: One-carbon metabolism]]
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[[Category: Oxidoreductase]]
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[[Category: Plasmid]]
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[[Category: Trimethoprim resistance]]
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Revision as of 04:05, 7 October 2022

STRUCTURE OF DIHYDROFOLATE REDUCTASE

PDB ID 1vie

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