4f1l

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==Human Artd8 (Parp14, Bal2) - catalytic domain in complex with inhibitor A16(Z)==
==Human Artd8 (Parp14, Bal2) - catalytic domain in complex with inhibitor A16(Z)==
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<StructureSection load='4f1l' size='340' side='right' caption='[[4f1l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='4f1l' size='340' side='right'caption='[[4f1l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4f1l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F1L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F1L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4f1l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F1L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F1L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0RY:(2Z)-4-[(3-CARBAMOYLPHENYL)AMINO]-4-OXOBUT-2-ENOIC+ACID'>0RY</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0RY:(2Z)-4-[(3-CARBAMOYLPHENYL)AMINO]-4-OXOBUT-2-ENOIC+ACID'>0RY</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4f1q|4f1q]], [[3smi|3smi]], [[3smj|3smj]], [[3se2|3se2]], [[3goy|3goy]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f1l OCA], [https://pdbe.org/4f1l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f1l RCSB], [https://www.ebi.ac.uk/pdbsum/4f1l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f1l ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAL2, KIAA1268, PARP14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f1l OCA], [http://pdbe.org/4f1l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f1l RCSB], [http://www.ebi.ac.uk/pdbsum/4f1l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f1l ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN]] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.
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[https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]]
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*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Andersson, C D]]
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[[Category: Large Structures]]
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[[Category: Ekblad, T]]
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[[Category: Andersson CD]]
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[[Category: Elofsson, M]]
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[[Category: Ekblad T]]
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[[Category: Karlberg, T]]
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[[Category: Elofsson M]]
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[[Category: Lindgren, A]]
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[[Category: Karlberg T]]
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[[Category: Linusson, A]]
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[[Category: Lindgren A]]
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[[Category: Schuler, H]]
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[[Category: Linusson A]]
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[[Category: Spjut, S]]
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[[Category: Schuler H]]
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[[Category: Thorsell, A G]]
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[[Category: Spjut S]]
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[[Category: Weigelt, J]]
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[[Category: Thorsell AG]]
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[[Category: Adp-ribose]]
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[[Category: Weigelt J]]
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[[Category: Adp-ribosylation]]
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[[Category: Artd transferase domain]]
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[[Category: Artd8]]
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[[Category: Bal2]]
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[[Category: Nad]]
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[[Category: Parp14]]
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[[Category: Transferase-transferase inhibitor complex]]
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Revision as of 04:28, 7 October 2022

Human Artd8 (Parp14, Bal2) - catalytic domain in complex with inhibitor A16(Z)

PDB ID 4f1l

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