4f6e

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==Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae==
==Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae==
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<StructureSection load='4f6e' size='340' side='right' caption='[[4f6e]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4f6e' size='340' side='right'caption='[[4f6e]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4f6e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F6E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F6E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4f6e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F6E FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SOD2, YHR008C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f6e OCA], [https://pdbe.org/4f6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f6e RCSB], [https://www.ebi.ac.uk/pdbsum/4f6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f6e ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f6e OCA], [http://pdbe.org/4f6e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f6e RCSB], [http://www.ebi.ac.uk/pdbsum/4f6e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f6e ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SODM_YEAST SODM_YEAST]] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
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[https://www.uniprot.org/uniprot/SODM_YEAST SODM_YEAST] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
==See Also==
==See Also==
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*[[Superoxide Dismutase|Superoxide Dismutase]]
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
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[[Category: Large Structures]]
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[[Category: Superoxide dismutase]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Cascio, D]]
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[[Category: Cascio D]]
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[[Category: Sheng, Y]]
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[[Category: Sheng Y]]
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[[Category: Valentine, J S]]
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[[Category: Valentine JS]]
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[[Category: Dimer interface]]
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[[Category: Mn superoxide dismutase]]
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[[Category: Oxidoreductase]]
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Revision as of 04:38, 7 October 2022

Crystal Structure of the K182R, A183P mutant manganese superoxide dismutase from Sacchromyces cerevisiae

PDB ID 4f6e

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