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4f96
From Proteopedia
(Difference between revisions)
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==Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP== | ==Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP== | ||
| - | <StructureSection load='4f96' size='340' side='right' caption='[[4f96]], [[Resolution|resolution]] 2.15Å' scene=''> | + | <StructureSection load='4f96' size='340' side='right'caption='[[4f96]], [[Resolution|resolution]] 2.15Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4f96]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4f96]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus_subsp._limoneus Streptomyces hygroscopicus subsp. limoneus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F96 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f96 OCA], [https://pdbe.org/4f96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f96 RCSB], [https://www.ebi.ac.uk/pdbsum/4f96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f96 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VLDE_STRHL VLDE_STRHL] Involved in the biosynthesis of the antifungal agent validamycin A (PubMed:16725283). Catalyzes the condensation between GDP-valienol and validamine 7-phosphate via a nonglycosidic C-N bond formation to yield validoxylamine A 7'-phosphate (PubMed:21766819).<ref>PMID:16725283</ref> <ref>PMID:21766819</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Streptomyces hygroscopicus subsp. limoneus | + | [[Category: Large Structures]] |
| - | [[Category: Almabruk | + | [[Category: Streptomyces hygroscopicus subsp. limoneus]] |
| - | [[Category: Asamizu | + | [[Category: Almabruk KH]] |
| - | [[Category: Cavalier | + | [[Category: Asamizu S]] |
| - | [[Category: Lee | + | [[Category: Cavalier MC]] |
| - | [[Category: Mahmud | + | [[Category: Lee Y-H]] |
| - | [[Category: Neau | + | [[Category: Mahmud T]] |
| - | [[Category: Yim | + | [[Category: Neau D]] |
| - | + | [[Category: Yim Y-S]] | |
| - | + | ||
Revision as of 04:42, 7 October 2022
Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP
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