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DNA Repair
From Proteopedia
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'''DNA Repair''' is necessary to maintain genome fidelity. Errors in DNA can arise from many different sources. Errors introduced in the replication process are the simplest source. This leads to non-Watson-Crick base pairs and local distortions in the helix. Bases can also be damaged by oxidizing agents, alkylating agents or UV light. This page will discuss different strategies for repairing these types of DNA damage. | '''DNA Repair''' is necessary to maintain genome fidelity. Errors in DNA can arise from many different sources. Errors introduced in the replication process are the simplest source. This leads to non-Watson-Crick base pairs and local distortions in the helix. Bases can also be damaged by oxidizing agents, alkylating agents or UV light. This page will discuss different strategies for repairing these types of DNA damage. | ||
| - | <StructureSection load= | + | <StructureSection load='B-DNA.pdb' size='350' side='right' scene='' caption=''> |
DNA forms an anti-parallel douuble helix. This is placeholder text. | DNA forms an anti-parallel douuble helix. This is placeholder text. | ||
Revision as of 20:20, 10 October 2022
The discussion on this page is targeted at genetics students, so familiarity with DNA structure, DNA Replication and Basics of Protein Structure is assumed.
DNA Repair is necessary to maintain genome fidelity. Errors in DNA can arise from many different sources. Errors introduced in the replication process are the simplest source. This leads to non-Watson-Crick base pairs and local distortions in the helix. Bases can also be damaged by oxidizing agents, alkylating agents or UV light. This page will discuss different strategies for repairing these types of DNA damage.
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For more structures, please see DNA Replication, Repair, and Recombination
References
Proteopedia Page Contributors and Editors (what is this?)
Ann Taylor, Casimiro Soliz, Michal Harel, Harry M. Snyder, Grant Johnson, Connor Wakefield, David Canner
