4fqa
From Proteopedia
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==Crystal structure of toxic effector Tse1== | ==Crystal structure of toxic effector Tse1== | ||
| - | <StructureSection load='4fqa' size='340' side='right' caption='[[4fqa]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='4fqa' size='340' side='right'caption='[[4fqa]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4fqa]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4fqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FQA FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqa OCA], [https://pdbe.org/4fqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fqa RCSB], [https://www.ebi.ac.uk/pdbsum/4fqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fqa ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa PAO1]] |
| - | [[Category: | + | [[Category: Li L]] |
| - | [[Category: | + | [[Category: Wang T]] |
| - | [[Category: | + | [[Category: Zhang W]] |
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Revision as of 20:05, 19 October 2022
Crystal structure of toxic effector Tse1
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