4fx7

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==Structure of Sym2 D9V+D55V+D130V+D176V==
==Structure of Sym2 D9V+D55V+D130V+D176V==
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<StructureSection load='4fx7' size='340' side='right' caption='[[4fx7]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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<StructureSection load='4fx7' size='340' side='right'caption='[[4fx7]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fx7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FX7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fx7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FX7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PI:HYDROGENPHOSPHATE+ION'>PI</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PI:HYDROGENPHOSPHATE+ION'>PI</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hisF, TM_1036 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fx7 OCA], [https://pdbe.org/4fx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fx7 RCSB], [https://www.ebi.ac.uk/pdbsum/4fx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fx7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fx7 OCA], [http://pdbe.org/4fx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fx7 RCSB], [http://www.ebi.ac.uk/pdbsum/4fx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fx7 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA]] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013]
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[https://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013]
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==See Also==
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*[[Indole-3-glycerol phosphate synthase|Indole-3-glycerol phosphate synthase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thema]]
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[[Category: Large Structures]]
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[[Category: Rajendran, C]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Sperl, J M]]
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[[Category: Rajendran C]]
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[[Category: Sterner, R]]
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[[Category: Sperl JM]]
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[[Category: De novo protein]]
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[[Category: Sterner R]]
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[[Category: Fusion protein]]
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[[Category: Lyase]]
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[[Category: Tim barrel]]
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Revision as of 20:14, 19 October 2022

Structure of Sym2 D9V+D55V+D130V+D176V

PDB ID 4fx7

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