4fyg

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==Structural basis for substrate recognition by a novel Legionella phosphoinositide phosphatase==
==Structural basis for substrate recognition by a novel Legionella phosphoinositide phosphatase==
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<StructureSection load='4fyg' size='340' side='right' caption='[[4fyg]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
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<StructureSection load='4fyg' size='340' side='right'caption='[[4fyg]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fyg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Legph Legph]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FYG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fyg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._Philadelphia_1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FYG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PT:(2R)-3-{[(S)-HYDROXY{[(1S,2R,3R,4S,5S,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIBUTANOATE'>3PT</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PT:(2R)-3-{[(S)-HYDROXY{[(1S,2R,3R,4S,5S,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIBUTANOATE'>3PT</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fye|4fye]], [[4fyf|4fyf]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyg OCA], [https://pdbe.org/4fyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fyg RCSB], [https://www.ebi.ac.uk/pdbsum/4fyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fyg ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpg2584, sidF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 LEGPH])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol-3,4,5-trisphosphate_3-phosphatase Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.67 3.1.3.67] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fyg OCA], [http://pdbe.org/4fyg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fyg RCSB], [http://www.ebi.ac.uk/pdbsum/4fyg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fyg ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5ZSD5_LEGPH Q5ZSD5_LEGPH]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Legph]]
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[[Category: Large Structures]]
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[[Category: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase]]
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[[Category: Legionella pneumophila subsp. pneumophila str. Philadelphia 1]]
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[[Category: Brennan, L]]
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[[Category: Brennan L]]
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[[Category: Hsu, F S]]
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[[Category: Hsu FS]]
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[[Category: Luo, Z Q]]
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[[Category: Luo ZQ]]
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[[Category: Mao, Y]]
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[[Category: Mao Y]]
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[[Category: Tao, L]]
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[[Category: Tao L]]
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[[Category: Zhu, W]]
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[[Category: Zhu W]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Mixed alpha-beta]]
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[[Category: Phosphoinositide phosphatase]]
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[[Category: Phosphoinositide]]
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Revision as of 20:15, 19 October 2022

Structural basis for substrate recognition by a novel Legionella phosphoinositide phosphatase

PDB ID 4fyg

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