7wqz
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Active-mutEP== | |
| - | + | <StructureSection load='7wqz' size='340' side='right'caption='[[7wqz]], [[Resolution|resolution]] 3.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7wqz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WQZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wqz OCA], [https://pdbe.org/7wqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wqz RCSB], [https://www.ebi.ac.uk/pdbsum/7wqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wqz ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Huang | + | == Disease == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/ENTK_HUMAN ENTK_HUMAN] Congenital enteropathy due to enteropeptidase deficiency. The disease is caused by mutations affecting the gene represented in this entry. |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ENTK_HUMAN ENTK_HUMAN] Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ding ZY]] | ||
| + | [[Category: Huang HJ]] | ||
| + | [[Category: Yang XL]] | ||
Revision as of 06:06, 26 October 2022
Structure of Active-mutEP
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