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4gcw

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==Crystal structure of RNase Z in complex with precursor tRNA(Thr)==
==Crystal structure of RNase Z in complex with precursor tRNA(Thr)==
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<StructureSection load='4gcw' size='340' side='right' caption='[[4gcw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='4gcw' size='340' side='right'caption='[[4gcw]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gcw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gcw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcw OCA], [https://pdbe.org/4gcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gcw RCSB], [https://www.ebi.ac.uk/pdbsum/4gcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcw ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1y44|1y44]], [[2fk6|2fk6]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU23840, rnz, yqjK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_Z Ribonuclease Z], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.11 3.1.26.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcw OCA], [http://pdbe.org/4gcw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gcw RCSB], [http://www.ebi.ac.uk/pdbsum/4gcw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcw ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNZ_BACSU RNZ_BACSU]] Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<ref>PMID:12941704</ref>
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[https://www.uniprot.org/uniprot/RNZ_BACSU RNZ_BACSU] Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<ref>PMID:12941704</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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*[[TRNA|TRNA]]
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*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
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*[[Temp|Temp]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsu]]
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[[Category: Bacillus subtilis]]
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[[Category: Ribonuclease Z]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Condon, C]]
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[[Category: Large Structures]]
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[[Category: Gilet, L]]
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[[Category: Condon C]]
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[[Category: Pellegrini, O]]
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[[Category: Gilet L]]
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[[Category: Piton, J]]
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[[Category: Li de la Sierra-Gallay I]]
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[[Category: Sierra-Gallay, I Li de la]]
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[[Category: Pellegrini O]]
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[[Category: Hydrolase-rna complex]]
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[[Category: Piton J]]
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[[Category: Protein-rna complex]]
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[[Category: Trna binding]]
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[[Category: Trna maturase]]
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[[Category: Zinc-dependent metalo betalactamase - rna complex]]
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Revision as of 06:48, 26 October 2022

Crystal structure of RNase Z in complex with precursor tRNA(Thr)

PDB ID 4gcw

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