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4gn2

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==Crystal Structure of OXA-45, a Class D beta-lactamase with extended spectrum activity==
==Crystal Structure of OXA-45, a Class D beta-lactamase with extended spectrum activity==
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<StructureSection load='4gn2' size='340' side='right' caption='[[4gn2]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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<StructureSection load='4gn2' size='340' side='right'caption='[[4gn2]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gn2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GN2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GN2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gn2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GN2 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaoxa45, oxa45 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gn2 OCA], [https://pdbe.org/4gn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gn2 RCSB], [https://www.ebi.ac.uk/pdbsum/4gn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gn2 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gn2 OCA], [http://pdbe.org/4gn2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gn2 RCSB], [http://www.ebi.ac.uk/pdbsum/4gn2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gn2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7WZC7_PSEAI Q7WZC7_PSEAI]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Catto, L E]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Clarke, A R]]
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[[Category: Catto LE]]
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[[Category: Martin, J D]]
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[[Category: Clarke AR]]
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[[Category: Spencer, J]]
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[[Category: Martin JD]]
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[[Category: Toleman, M A]]
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[[Category: Spencer J]]
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[[Category: Walsh, T R]]
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[[Category: Toleman MA]]
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[[Category: Xiong, X L]]
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[[Category: Walsh TR]]
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[[Category: Alpha/beta]]
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[[Category: Xiong XL]]
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[[Category: Antibiotic resistance]]
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[[Category: Hydrolase]]
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[[Category: Lysine carbamylation]]
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Revision as of 07:06, 26 October 2022

Crystal Structure of OXA-45, a Class D beta-lactamase with extended spectrum activity

PDB ID 4gn2

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