4gom
From Proteopedia
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==Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Aza-SAM== | ==Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Aza-SAM== | ||
| - | <StructureSection load='4gom' size='340' side='right' caption='[[4gom]], [[Resolution|resolution]] 2.45Å' scene=''> | + | <StructureSection load='4gom' size='340' side='right'caption='[[4gom]], [[Resolution|resolution]] 2.45Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gom]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4gom]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GOM FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0Y0:5-{[(3S)-3-AMINO-3-CARBOXYPROPYL]AMINO}-5-DEOXYADENOSINE'>0Y0</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0Y0:5-{[(3S)-3-AMINO-3-CARBOXYPROPYL]AMINO}-5-DEOXYADENOSINE'>0Y0</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gom OCA], [https://pdbe.org/4gom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gom RCSB], [https://www.ebi.ac.uk/pdbsum/4gom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gom ProSAT]</span></td></tr> | |
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| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DMA_ECOLI DMA_ECOLI] Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication. |
==See Also== | ==See Also== | ||
*[[DNA adenine methylase|DNA adenine methylase]] | *[[DNA adenine methylase|DNA adenine methylase]] | ||
| + | *[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Harmer JE]] |
| - | [[Category: | + | [[Category: Roach PL]] |
| - | + | ||
Revision as of 07:08, 26 October 2022
Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Aza-SAM
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