4gwr

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==Crystal Structure of the second catalytic domain of protein disulfide isomerase P5==
==Crystal Structure of the second catalytic domain of protein disulfide isomerase P5==
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<StructureSection load='4gwr' size='340' side='right' caption='[[4gwr]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
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<StructureSection load='4gwr' size='340' side='right'caption='[[4gwr]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gwr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GWR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gwr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GWR FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDIA6, ERP5, P5, TXNDC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwr OCA], [https://pdbe.org/4gwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gwr RCSB], [https://www.ebi.ac.uk/pdbsum/4gwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwr ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_disulfide-isomerase Protein disulfide-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.4.1 5.3.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwr OCA], [http://pdbe.org/4gwr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gwr RCSB], [http://www.ebi.ac.uk/pdbsum/4gwr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwr ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PDIA6_HUMAN PDIA6_HUMAN]] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.<ref>PMID:15466936</ref> <ref>PMID:12204115</ref>
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[https://www.uniprot.org/uniprot/PDIA6_HUMAN PDIA6_HUMAN] May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.<ref>PMID:15466936</ref> <ref>PMID:12204115</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Protein disulfide-isomerase]]
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[[Category: Large Structures]]
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[[Category: Gehring, K]]
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[[Category: Gehring K]]
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[[Category: Kozlov, G]]
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[[Category: Kozlov G]]
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[[Category: Vinaik, R]]
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[[Category: Vinaik R]]
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[[Category: Bip]]
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[[Category: Disulfide isomerase]]
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[[Category: Endoplasmic reticulum]]
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[[Category: Isomerase]]
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[[Category: Thioredoxin-like fold]]
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Revision as of 07:23, 26 October 2022

Crystal Structure of the second catalytic domain of protein disulfide isomerase P5

PDB ID 4gwr

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