This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4gyq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal Structure of New Delhi Metallo-beta-Lactamase-1 D223A mutant from Klebsiella pneumoniae==
==Crystal Structure of New Delhi Metallo-beta-Lactamase-1 D223A mutant from Klebsiella pneumoniae==
-
<StructureSection load='4gyq' size='340' side='right' caption='[[4gyq]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
+
<StructureSection load='4gyq' size='340' side='right'caption='[[4gyq]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4gyq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GYQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GYQ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4gyq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GYQ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rkj|3rkj]], [[3rkk|3rkk]], [[3sbl|3sbl]], [[3sfp|3sfp]], [[3srx|3srx]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gyq OCA], [https://pdbe.org/4gyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gyq RCSB], [https://www.ebi.ac.uk/pdbsum/4gyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gyq ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaNDM-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gyq OCA], [http://pdbe.org/4gyq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gyq RCSB], [http://www.ebi.ac.uk/pdbsum/4gyq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gyq ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN]] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
+
[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
 +
 
 +
==See Also==
 +
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
+
[[Category: Klebsiella pneumoniae]]
-
[[Category: Babnigg, J]]
+
[[Category: Large Structures]]
-
[[Category: Binkowski, T A]]
+
[[Category: Babnigg J]]
-
[[Category: Jedrzejczak, R]]
+
[[Category: Binkowski TA]]
-
[[Category: Joachimiak, A]]
+
[[Category: Jedrzejczak R]]
-
[[Category: Kim, Y]]
+
[[Category: Joachimiak A]]
 +
[[Category: Kim Y]]
[[Category: MCSG]]
[[Category: MCSG]]
-
[[Category: Structural genomic]]
+
[[Category: Mire J]]
-
[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors]]
+
[[Category: Sacchettini J]]
-
[[Category: Mire, J]]
+
[[Category: Tesar C]]
-
[[Category: Sacchettini, J]]
+
-
[[Category: Tesar, C]]
+
-
[[Category: Alpha-beta-beta-alpha fold]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Mcsg]]
+
-
[[Category: Mtbi]]
+
-
[[Category: Psi-biology]]
+
-
[[Category: Structures of mtb proteins conferring susceptibility to known mtb inhibitor]]
+

Revision as of 07:27, 26 October 2022

Crystal Structure of New Delhi Metallo-beta-Lactamase-1 D223A mutant from Klebsiella pneumoniae

PDB ID 4gyq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4gyq"
Personal tools