7xi4

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'''Unreleased structure'''
 
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The entry 7xi4 is ON HOLD until Paper Publication
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==Crystal Structure of the NPAS4-ARNT heterodimer in complex with DNA==
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<StructureSection load='7xi4' size='340' side='right'caption='[[7xi4]], [[Resolution|resolution]] 4.71&Aring;' scene=''>
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Authors: Sun, X.N., Jing, L.Q., Li, F.W., Wu, D.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7xi4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XI4 FirstGlance]. <br>
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Description: Crystal Structure of the NPAS4-ARNT heterodimer in complex with DNA
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xi4 OCA], [https://pdbe.org/7xi4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xi4 RCSB], [https://www.ebi.ac.uk/pdbsum/7xi4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xi4 ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Jing, L.Q]]
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== Function ==
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[[Category: Wu, D.L]]
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[https://www.uniprot.org/uniprot/ARNT_MOUSE ARNT_MOUSE] Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity).
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[[Category: Sun, X.N]]
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__TOC__
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[[Category: Li, F.W]]
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Jing LQ]]
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[[Category: Li FW]]
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[[Category: Sun XN]]
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[[Category: Wu DL]]

Revision as of 07:18, 3 November 2022

Crystal Structure of the NPAS4-ARNT heterodimer in complex with DNA

PDB ID 7xi4

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