This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4hac

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:07, 3 November 2022) (edit) (undo)
 
Line 1: Line 1:
==Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei==
==Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei==
-
<StructureSection load='4hac' size='340' side='right' caption='[[4hac]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
+
<StructureSection load='4hac' size='340' side='right'caption='[[4hac]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4hac]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Metma Metma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HAC FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4hac]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_mazei_Go1 Methanosarcina mazei Go1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HAC FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hac OCA], [https://pdbe.org/4hac PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hac RCSB], [https://www.ebi.ac.uk/pdbsum/4hac PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hac ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MM_1762, MVK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192952 METMA])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mevalonate_kinase Mevalonate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.36 2.7.1.36] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hac FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hac OCA], [http://pdbe.org/4hac PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hac RCSB], [http://www.ebi.ac.uk/pdbsum/4hac PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hac ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/Q8PW39_METMA Q8PW39_METMA]] Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.[HAMAP-Rule:MF_00217]
+
[https://www.uniprot.org/uniprot/Q8PW39_METMA Q8PW39_METMA] Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.[HAMAP-Rule:MF_00217]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 18:
</div>
</div>
<div class="pdbe-citations 4hac" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4hac" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Mevalonate kinase|Mevalonate kinase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Metma]]
+
[[Category: Large Structures]]
-
[[Category: Mevalonate kinase]]
+
[[Category: Methanosarcina mazei Go1]]
-
[[Category: Lee, K H]]
+
[[Category: Lee KH]]
-
[[Category: Zhuang, N]]
+
[[Category: Zhuang N]]
-
[[Category: Atp binding]]
+
-
[[Category: Ghmp]]
+
-
[[Category: Phosphorylation]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei

PDB ID 4hac

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4hac"
Personal tools