4hb7

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==The Structure of Dihydropteroate Synthase from Staphylococcus aureus subsp. aureus Mu50.==
==The Structure of Dihydropteroate Synthase from Staphylococcus aureus subsp. aureus Mu50.==
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<StructureSection load='4hb7' size='340' side='right' caption='[[4hb7]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4hb7' size='340' side='right'caption='[[4hb7]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hb7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HB7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HB7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hb7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HB7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HB7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">folP, SAV0514 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hb7 OCA], [https://pdbe.org/4hb7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hb7 RCSB], [https://www.ebi.ac.uk/pdbsum/4hb7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hb7 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropteroate_synthase Dihydropteroate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.15 2.5.1.15] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hb7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hb7 OCA], [http://pdbe.org/4hb7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hb7 RCSB], [http://www.ebi.ac.uk/pdbsum/4hb7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hb7 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DHPS_STAAM DHPS_STAAM]] DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide.
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[https://www.uniprot.org/uniprot/DHPS_STAAM DHPS_STAAM] DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide.
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==See Also==
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*[[Dihydropteroate synthase 3D structures|Dihydropteroate synthase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dihydropteroate synthase]]
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[[Category: Large Structures]]
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[[Category: Staam]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Baker, D]]
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[[Category: Baker D]]
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[[Category: Cuff, M E]]
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[[Category: Cuff ME]]
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[[Category: Guinn, K]]
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[[Category: Guinn K]]
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[[Category: Holowicki, J]]
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[[Category: Holowicki J]]
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[[Category: Ioerger, T R]]
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[[Category: Ioerger TR]]
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[[Category: Jedrzejczak, R]]
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[[Category: Jedrzejczak R]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Structural genomic]]
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[[Category: Rubin EJ]]
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[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors]]
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[[Category: Sacchettini JC]]
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[[Category: Rubin, E J]]
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[[Category: Terwilliger TC]]
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[[Category: Sacchettini, J C]]
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[[Category: Terwilliger, T C]]
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[[Category: Mcsg]]
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[[Category: Mtbi]]
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[[Category: Psi-biology]]
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[[Category: Structures of mtb proteins conferring susceptibility to known mtb inhibitor]]
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[[Category: Transferase]]
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Revision as of 08:08, 3 November 2022

The Structure of Dihydropteroate Synthase from Staphylococcus aureus subsp. aureus Mu50.

PDB ID 4hb7

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