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4hcx

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==Structure of ICDH-1 from M.tuberculosis complexed with NADPH & Mn2+==
==Structure of ICDH-1 from M.tuberculosis complexed with NADPH & Mn2+==
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<StructureSection load='4hcx' size='340' side='right' caption='[[4hcx]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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<StructureSection load='4hcx' size='340' side='right'caption='[[4hcx]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hcx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HCX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hcx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HCX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">icd, Rv3339c, MT3442, MTV016.39c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcx OCA], [https://pdbe.org/4hcx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hcx RCSB], [https://www.ebi.ac.uk/pdbsum/4hcx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hcx ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcx OCA], [http://pdbe.org/4hcx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hcx RCSB], [http://www.ebi.ac.uk/pdbsum/4hcx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hcx ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IDH_MYCTU IDH_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]]
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*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Blanchard, J]]
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[[Category: Large Structures]]
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[[Category: Hazra, S]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Dehydrogenase]]
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[[Category: Blanchard J]]
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[[Category: Icdh-1]]
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[[Category: Hazra S]]
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[[Category: Nadp binding]]
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[[Category: Oxidoreductase]]
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[[Category: Rossmann fold]]
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Revision as of 08:10, 3 November 2022

Structure of ICDH-1 from M.tuberculosis complexed with NADPH & Mn2+

PDB ID 4hcx

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