1ixg

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[[Image:1ixg.gif|left|200px]]
[[Image:1ixg.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1ixg |SIZE=350|CAPTION= <scene name='initialview01'>1ixg</scene>, resolution 1.05&Aring;
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The line below this paragraph, containing "STRUCTURE_1ixg", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= PHO-S ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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-->
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|DOMAIN=
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{{STRUCTURE_1ixg| PDB=1ixg | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ixg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixg OCA], [http://www.ebi.ac.uk/pdbsum/1ixg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ixg RCSB]</span>
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}}
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'''PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE'''
'''PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE'''
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[[Category: Quiocho, F A.]]
[[Category: Quiocho, F A.]]
[[Category: Wang, Z.]]
[[Category: Wang, Z.]]
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[[Category: phosphate bindin protein]]
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[[Category: Phosphate bindin protein]]
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[[Category: phosphate transport]]
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[[Category: Phosphate transport]]
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[[Category: ultra high resolution]]
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[[Category: Ultra high resolution]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:32:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:26:01 2008''
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Revision as of 17:32, 2 May 2008

Image:1ixg.gif

Template:STRUCTURE 1ixg

PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE


Overview

A very short hydrogen bond between an Asp and a phosphate is established in two high resolution structures (0.98 and 1.05 A). A mutant complex that changes the Asp to an Asn, which forms a normal hydrogen bond, has a similar free energy of binding to the wild type complex, suggesting that the contribution of the short hydrogen bond is not extraordinarily strong.

About this Structure

1IXG is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes., Wang Z, Luecke H, Yao N, Quiocho FA, Nat Struct Biol. 1997 Jul;4(7):519-22. PMID:9228942 Page seeded by OCA on Fri May 2 20:32:40 2008

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OCA

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