4hr2

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==Structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to ADP==
==Structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to ADP==
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<StructureSection load='4hr2' size='340' side='right' caption='[[4hr2]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4hr2' size='340' side='right'caption='[[4hr2]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hr2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burta Burta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HR2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_thailandensis_E264 Burkholderia thailandensis E264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HR2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dut|4dut]], [[4ek2|4ek2]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hr2 OCA], [https://pdbe.org/4hr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hr2 RCSB], [https://www.ebi.ac.uk/pdbsum/4hr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hr2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ndk, BTH_I2231 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 BURTA])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hr2 OCA], [http://pdbe.org/4hr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hr2 RCSB], [http://www.ebi.ac.uk/pdbsum/4hr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hr2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NDK_BURTA NDK_BURTA]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
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[https://www.uniprot.org/uniprot/NDK_BURTA NDK_BURTA] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
==See Also==
==See Also==
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*[[Nucleoside diphosphate kinase|Nucleoside diphosphate kinase]]
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*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Burta]]
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[[Category: Burkholderia thailandensis E264]]
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[[Category: Nucleoside-diphosphate kinase]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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Revision as of 08:06, 9 November 2022

Structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to ADP

PDB ID 4hr2

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