4hr7

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==Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli==
==Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli==
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<StructureSection load='4hr7' size='340' side='right' caption='[[4hr7]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4hr7' size='340' side='right'caption='[[4hr7]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hr7]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HR7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HR7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hr7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HR7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1dv1|1dv1]], [[1bdo|1bdo]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hr7 OCA], [https://pdbe.org/4hr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hr7 RCSB], [https://www.ebi.ac.uk/pdbsum/4hr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hr7 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">accC, fabG, b3256, JW3224 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12]), accB, fabE, b3255, JW3223 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hr7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hr7 RCSB], [http://www.ebi.ac.uk/pdbsum/4hr7 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACCC_ECOLI ACCC_ECOLI]] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. [[http://www.uniprot.org/uniprot/BCCP_ECOLI BCCP_ECOLI]] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
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[https://www.uniprot.org/uniprot/ACCC_ECOLI ACCC_ECOLI] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4hr7" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Biotin carboxylase|Biotin carboxylase]]
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*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli k-12]]
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[[Category: Escherichia coli K-12]]
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[[Category: Broussard, T C]]
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[[Category: Large Structures]]
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[[Category: Champion, T S]]
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[[Category: Broussard TC]]
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[[Category: Kobe, M J]]
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[[Category: Champion TS]]
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[[Category: Neau, D B]]
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[[Category: Kobe MJ]]
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[[Category: Pakhomova, S]]
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[[Category: Neau DB]]
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[[Category: Price, A E]]
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[[Category: Pakhomova S]]
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[[Category: Waldrop, G L]]
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[[Category: Price AE]]
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[[Category: Acetyl-coa carboxylase]]
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[[Category: Waldrop GL]]
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[[Category: Antibiotic target]]
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[[Category: Atp grasp]]
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[[Category: Biotin carboxyl carrier protein]]
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[[Category: Biotin carboxylase]]
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[[Category: Biotin-dependent carboxylase]]
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[[Category: Fatty acid synthesis]]
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[[Category: Ligase-biotin binding protein complex]]
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[[Category: Protein complex]]
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[[Category: Protein interface]]
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[[Category: Protein-protein interaction]]
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Revision as of 08:06, 9 November 2022

Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli

PDB ID 4hr7

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