4htf

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==Crystal structure of S-adenosylmethionine-dependent methyltransferase from Escherichia coli in complex with S-adenosylmethionine.==
==Crystal structure of S-adenosylmethionine-dependent methyltransferase from Escherichia coli in complex with S-adenosylmethionine.==
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<StructureSection load='4htf' size='340' side='right' caption='[[4htf]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4htf' size='340' side='right'caption='[[4htf]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4htf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HTF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4htf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HTF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4htf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htf OCA], [https://pdbe.org/4htf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4htf RCSB], [https://www.ebi.ac.uk/pdbsum/4htf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4htf ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAB34427, ECs1004, smtA, Z1268 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4htf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4htf OCA], [http://pdbe.org/4htf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4htf RCSB], [http://www.ebi.ac.uk/pdbsum/4htf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4htf ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CMOM_ECO57 CMOM_ECO57] Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.[HAMAP-Rule:MF_02057]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Eco57]]
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[[Category: Escherichia coli O157:H7]]
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[[Category: Anderson, W F]]
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[[Category: Large Structures]]
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[[Category: Filippova, E V]]
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[[Category: Anderson WF]]
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[[Category: Jedrzejczak, R]]
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[[Category: Filippova EV]]
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[[Category: Joachimiak, A]]
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[[Category: Jedrzejczak R]]
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[[Category: Kiryukhina, O]]
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[[Category: Joachimiak A]]
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[[Category: Structural genomic]]
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[[Category: Kiryukhina O]]
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[[Category: Minasov, G]]
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[[Category: Minasov G]]
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[[Category: Shuvalova, L]]
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[[Category: Shuvalova L]]
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[[Category: Mcsg]]
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[[Category: Psi-biology]]
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[[Category: Transferase]]
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Revision as of 08:12, 9 November 2022

Crystal structure of S-adenosylmethionine-dependent methyltransferase from Escherichia coli in complex with S-adenosylmethionine.

PDB ID 4htf

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