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4hua

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==E. coli thioredoxin variant with (4R)-FluoroPro76 as single proline residue==
==E. coli thioredoxin variant with (4R)-FluoroPro76 as single proline residue==
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<StructureSection load='4hua' size='340' side='right' caption='[[4hua]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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<StructureSection load='4hua' size='340' side='right'caption='[[4hua]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HUA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HUA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=FP9:(4R)-4-FLUORO-L-PROLINE'>FP9</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FP9:(4R)-4-FLUORO-L-PROLINE'>FP9</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hua OCA], [https://pdbe.org/4hua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hua RCSB], [https://www.ebi.ac.uk/pdbsum/4hua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hua ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hu7|4hu7]], [[4hu9|4hu9]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trxA, fipA, tsnC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hua OCA], [http://pdbe.org/4hua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hua RCSB], [http://www.ebi.ac.uk/pdbsum/4hua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hua ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
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[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4hua" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4hua" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Capitani, G]]
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[[Category: Large Structures]]
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[[Category: Glockshuber, R]]
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[[Category: Capitani G]]
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[[Category: Rubini, M]]
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[[Category: Glockshuber R]]
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[[Category: Scharer, M A]]
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[[Category: Rubini M]]
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[[Category: 4r-fluoroproline]]
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[[Category: Scharer MA]]
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[[Category: Cisproline]]
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[[Category: Oxidoreductase]]
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[[Category: Protein disulfide oxidoreductase activity]]
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[[Category: Thioredoxin fold]]
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Revision as of 08:15, 9 November 2022

E. coli thioredoxin variant with (4R)-FluoroPro76 as single proline residue

PDB ID 4hua

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