4hv4

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==2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP==
==2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP==
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<StructureSection load='4hv4' size='340' side='right' caption='[[4hv4]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='4hv4' size='340' side='right'caption='[[4hv4]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hv4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HV4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HV4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hv4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HV4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HV4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">murC, y3625, YPO0556, YP_3628 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hv4 OCA], [https://pdbe.org/4hv4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hv4 RCSB], [https://www.ebi.ac.uk/pdbsum/4hv4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hv4 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramate--L-alanine_ligase UDP-N-acetylmuramate--L-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.8 6.3.2.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hv4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hv4 OCA], [http://pdbe.org/4hv4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hv4 RCSB], [http://www.ebi.ac.uk/pdbsum/4hv4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hv4 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MURC_YERPE MURC_YERPE]] Cell wall formation.[HAMAP-Rule:MF_00046]
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[https://www.uniprot.org/uniprot/MURC_YERPE MURC_YERPE] Cell wall formation.[HAMAP-Rule:MF_00046]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: UDP-N-acetylmuramate--L-alanine ligase]]
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[[Category: Large Structures]]
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[[Category: Yersinia pestis co92]]
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[[Category: Yersinia pestis CO92]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Dubrovska I]]
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[[Category: Dubrovska, I]]
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[[Category: Halavaty AS]]
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[[Category: Halavaty, A S]]
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[[Category: Minasov G]]
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[[Category: Minasov, G]]
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[[Category: Peterson S]]
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[[Category: Peterson, S]]
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[[Category: Shuvalova L]]
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[[Category: Shuvalova, L]]
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[[Category: Winsor J]]
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[[Category: Winsor, J]]
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[[Category: Ligase]]
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[[Category: Murc]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Peptidoglycan synthesis]]
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[[Category: Udp-n-acetylmuramate-l-alanine ligase]]
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Revision as of 08:17, 9 November 2022

2.25 Angstrom resolution crystal structure of UDP-N-acetylmuramate--L-alanine ligase (murC) from Yersinia pestis CO92 in complex with AMP

PDB ID 4hv4

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