This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4i16

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Crystal structure of CARMA1 CARD==
==Crystal structure of CARMA1 CARD==
-
<StructureSection load='4i16' size='340' side='right' caption='[[4i16]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
+
<StructureSection load='4i16' size='340' side='right'caption='[[4i16]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4i16]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4I16 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4i16]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I16 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Card11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i16 OCA], [https://pdbe.org/4i16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i16 RCSB], [https://www.ebi.ac.uk/pdbsum/4i16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i16 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i16 OCA], [http://pdbe.org/4i16 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4i16 RCSB], [http://www.ebi.ac.uk/pdbsum/4i16 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4i16 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CAR11_MOUSE CAR11_MOUSE]] Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10 (By similarity).
+
[https://www.uniprot.org/uniprot/CAR11_MOUSE CAR11_MOUSE] Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10 (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Large Structures]]
-
[[Category: Li, S]]
+
[[Category: Mus musculus]]
-
[[Category: Shen, Y]]
+
[[Category: Li S]]
-
[[Category: Yang, X]]
+
[[Category: Shen Y]]
-
[[Category: Bcl10 and malt1 binding]]
+
[[Category: Yang X]]
-
[[Category: Cbm complex]]
+
-
[[Category: Helix bundle]]
+
-
[[Category: Phosphorylation]]
+
-
[[Category: Scaffold protein]]
+
-
[[Category: Signaling protein]]
+

Revision as of 08:33, 9 November 2022

Crystal structure of CARMA1 CARD

PDB ID 4i16

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4i16"
Personal tools