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4iv1

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==Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid==
==Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid==
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<StructureSection load='4iv1' size='340' side='right' caption='[[4iv1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4iv1' size='340' side='right'caption='[[4iv1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4iv1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphthovirus_a Aphthovirus a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IV1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4iv1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_A Foot-and-mouth disease virus A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IV1 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FMDV A22 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12111 Aphthovirus A])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iv1 OCA], [https://pdbe.org/4iv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iv1 RCSB], [https://www.ebi.ac.uk/pdbsum/4iv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iv1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iv1 OCA], [http://pdbe.org/4iv1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4iv1 RCSB], [http://www.ebi.ac.uk/pdbsum/4iv1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4iv1 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q6PN23_9PICO Q6PN23_9PICO]] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
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[https://www.uniprot.org/uniprot/Q6PN23_9PICO Q6PN23_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4iv1" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4iv1" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aphthovirus a]]
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[[Category: Foot-and-mouth disease virus A]]
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[[Category: Burman, A]]
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[[Category: Large Structures]]
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[[Category: Charleston, B]]
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[[Category: Burman A]]
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[[Category: Fry, E E]]
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[[Category: Charleston B]]
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[[Category: Jackson, T]]
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[[Category: Fry EE]]
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[[Category: Jones, I M]]
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[[Category: Jackson T]]
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[[Category: Kotecha, A]]
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[[Category: Jones IM]]
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[[Category: Loureiro, S]]
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[[Category: Kotecha A]]
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[[Category: Porta, C]]
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[[Category: Loureiro S]]
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[[Category: Ren, J]]
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[[Category: Porta C]]
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[[Category: Stuart, D I]]
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[[Category: Ren J]]
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[[Category: Apthovirus]]
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[[Category: Stuart DI]]
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[[Category: Capsid]]
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[[Category: Icosahedral virus]]
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[[Category: Picornavirus]]
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[[Category: Vaccine]]
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[[Category: Virus]]
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Revision as of 21:13, 16 November 2022

Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid

PDB ID 4iv1

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