4ixd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution==
==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution==
-
<StructureSection load='4ixd' size='340' side='right' caption='[[4ixd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+
<StructureSection load='4ixd' size='340' side='right'caption='[[4ixd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IXD FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IXD FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xdg|1xdg]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ixd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixd OCA], [https://pdbe.org/4ixd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ixd RCSB], [https://www.ebi.ac.uk/pdbsum/4ixd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ixd ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ITGAL, CD11A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ixd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixd OCA], [http://pdbe.org/4ixd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ixd RCSB], [http://www.ebi.ac.uk/pdbsum/4ixd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ixd ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN]] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
+
[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
==See Also==
==See Also==
-
*[[Integrin|Integrin]]
+
*[[Integrin 3D structures|Integrin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Kallen, J]]
+
[[Category: Large Structures]]
-
[[Category: I-domain]]
+
[[Category: Kallen J]]
-
[[Category: Immune system]]
+
-
[[Category: Rossman-fold]]
+

Revision as of 21:17, 16 November 2022

X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution

PDB ID 4ixd

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools