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4j2c

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==GARP-SNARE Interaction==
==GARP-SNARE Interaction==
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<StructureSection load='4j2c' size='340' side='right' caption='[[4j2c]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='4j2c' size='340' side='right'caption='[[4j2c]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4j2c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J2C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4j2c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2C FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STX6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2c OCA], [https://pdbe.org/4j2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2c RCSB], [https://www.ebi.ac.uk/pdbsum/4j2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2c OCA], [http://pdbe.org/4j2c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j2c RCSB], [http://www.ebi.ac.uk/pdbsum/4j2c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2c ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STX6_HUMAN STX6_HUMAN]] Involved in intracellular vesicle trafficking. [[http://www.uniprot.org/uniprot/VPS51_HUMAN VPS51_HUMAN]] Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi networkl (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN.<ref>PMID:20685960</ref>
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[https://www.uniprot.org/uniprot/STX6_HUMAN STX6_HUMAN] Involved in intracellular vesicle trafficking.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4j2c" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4j2c" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Syntaxin 3D structures|Syntaxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Abascal-Palacios, G]]
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[[Category: Large Structures]]
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[[Category: Bonifacino, J S]]
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[[Category: Abascal-Palacios G]]
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[[Category: Hierro, A]]
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[[Category: Bonifacino JS]]
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[[Category: Rojas, A L]]
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[[Category: Hierro A]]
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[[Category: Schindler, C]]
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[[Category: Rojas AL]]
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[[Category: Protein transport]]
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[[Category: Schindler C]]
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[[Category: Tethering complex]]
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Revision as of 21:27, 16 November 2022

GARP-SNARE Interaction

PDB ID 4j2c

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