Gluconeogenesis
From Proteopedia
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'''Under development!''' | '''Under development!''' | ||
| - | Gluconeogenesis is a metabolic pathway that results in the generation of glucose from certain non-carbohydrate carbon substrates. [[Phosphoglycerate Kinase|Phosphoglycerate kinase]] is an enzyme that catalyzes the reversible transfer of a phosphate group from 1,3-bisphosphoglycerate (1,3-BPG) to ADP producing 3-phosphoglycerate (3-PG) and ATP : | + | Gluconeogenesis is a metabolic pathway that results in the generation of glucose from certain non-carbohydrate carbon substrates. [[Phosphoglycerate Kinase|Phosphoglycerate kinase]] is an enzyme that catalyzes the reversible transfer of a phosphate group from <scene name='39/392339/Cv1/5'>1,3-bisphosphoglycerate (1,3-BPG)</scene> to ADP producing <scene name='39/392339/Cv1/6'>3-phosphoglycerate (3-PG)</scene> and ATP: |
1,3-bisphosphoglycerate + ADP ⇌ glycerate 3-phosphate + ATP | 1,3-bisphosphoglycerate + ADP ⇌ glycerate 3-phosphate + ATP | ||
| - | Like all kinases it is a transferase. PGK is a major enzyme used in glycolysis, in the first ATP-generating step of the glycolytic pathway. In '''gluconeogenesis''', the reaction catalyzed by PGK proceeds in the opposite direction, generating ADP and | + | Like all kinases it is a transferase. PGK is a major enzyme used in glycolysis, in the first ATP-generating step of the glycolytic pathway. In '''gluconeogenesis''', the reaction catalyzed by PGK proceeds in the opposite direction, generating ADP and 3-phosphoglycerate (3-PG) |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 11:51, 21 November 2022
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