Gluconeogenesis

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1,3-bisphosphoglycerate + ADP ⇌ glycerate 3-phosphate + ATP
1,3-bisphosphoglycerate + ADP ⇌ glycerate 3-phosphate + ATP
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Like all kinases it is a transferase. PGK is a major enzyme used in glycolysis, in the first ATP-generating step of the glycolytic pathway. In '''gluconeogenesis''', the reaction catalyzed by PGK proceeds in the opposite direction, generating ADP and 3-phosphoglycerate (3-PG)
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Like all kinases it is a transferase. PGK is a major enzyme used in glycolysis, in the first ATP-generating step of the glycolytic pathway. In gluconeogenesis, the reaction catalyzed by PGK proceeds in the opposite direction, generating ADP and 3-phosphoglycerate (3-PG)
</StructureSection>
</StructureSection>
== References ==
== References ==
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<references/>

Revision as of 13:04, 22 November 2022

Human phosphoglycerate kinase complex with phosphoglyceric acid, ADP (stick model) AlF4-, Cl- and Mg+2 ions (green) (PDB code 2y3i)

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References

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky

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