7yg4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 7yg4 is ON HOLD until Paper Publication
+
==Structure of WTAP-VIRMA in the m6A writer complex==
-
 
+
<StructureSection load='7yg4' size='340' side='right'caption='[[7yg4]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[7yg4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YG4 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yg4 OCA], [https://pdbe.org/7yg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yg4 RCSB], [https://www.ebi.ac.uk/pdbsum/7yg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yg4 ProSAT]</span></td></tr>
-
[[Category: Unreleased Structures]]
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/VIR_HUMAN VIR_HUMAN] Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:24981863, PubMed:29507755). Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites (PubMed:29507755). Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA) (PubMed:29507755).<ref>PMID:24981863</ref> <ref>PMID:29507755</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Guan ZY]]
 +
[[Category: Tang C]]
 +
[[Category: Yan XH]]
 +
[[Category: Yin P]]

Revision as of 10:10, 24 November 2022

Structure of WTAP-VIRMA in the m6A writer complex

PDB ID 7yg4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7yg4"
Personal tools