8f2f

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m (Protected "8f2f" [edit=sysop:move=sysop])
Current revision (10:16, 24 November 2022) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8f2f is ON HOLD
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==NMR solution structure of lambda-MeuKTx-1==
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<StructureSection load='8f2f' size='340' side='right'caption='[[8f2f]]' scene=''>
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Authors: Harvey, P.J., Craik, D.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8f2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_eupeus Mesobuthus eupeus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F2F FirstGlance]. <br>
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Description: NMR solution structure of lambda-MeuKTx-1
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f2f OCA], [https://pdbe.org/8f2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f2f RCSB], [https://www.ebi.ac.uk/pdbsum/8f2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f2f ProSAT]</span></td></tr>
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[[Category: Craik, D.J]]
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</table>
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[[Category: Harvey, P.J]]
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== Function ==
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[https://www.uniprot.org/uniprot/CLML_MESEU CLML_MESEU] Voltage-gated potassium channel (Kv) inhibitor (Ref.2). In addition it may increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells (By similarity).[UniProtKB:P0DM29][UniProtKB:P59868]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mesobuthus eupeus]]
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[[Category: Craik DJ]]
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[[Category: Harvey PJ]]

Current revision

NMR solution structure of lambda-MeuKTx-1

PDB ID 8f2f

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