7ppx
From Proteopedia
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== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN] May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref> | |
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| + | ==See Also== | ||
| + | *[[ATPase family AAA domain-containing protein|ATPase family AAA domain-containing protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 10:23, 24 November 2022
ATAD2 in complex with FragLite3
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Categories: Homo sapiens | Large Structures | Endicott JA | Heath R | Hope I | Martin MP | Ng YM | Noble MEM | Turberville S | Wood DJ
