We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

4j6g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==CRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX==
==CRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX==
-
<StructureSection load='4j6g' size='340' side='right' caption='[[4j6g]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+
<StructureSection load='4j6g' size='340' side='right'caption='[[4j6g]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4j6g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J6G FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4j6g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J6G FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4en0|4en0]], [[3k51|3k51]], [[3mi8|3mi8]], [[3mhd|3mhd]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j6g OCA], [https://pdbe.org/4j6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j6g RCSB], [https://www.ebi.ac.uk/pdbsum/4j6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j6g ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNFSF14, HVEML, LIGHT, UNQ391/PRO726 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), TNFRSF6B, DCR3, TR6, UNQ186/PRO212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j6g OCA], [http://pdbe.org/4j6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j6g RCSB], [http://www.ebi.ac.uk/pdbsum/4j6g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j6g ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN]] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. [[http://www.uniprot.org/uniprot/TNF6B_HUMAN TNF6B_HUMAN]] Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.<ref>PMID:21300286</ref>
+
[https://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 20:
==See Also==
==See Also==
-
*[[Tumor necrosis factor receptor|Tumor necrosis factor receptor]]
+
*[[Tumor necrosis factor ligand superfamily 3D structures|Tumor necrosis factor ligand superfamily 3D structures]]
 +
*[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Almo, S C]]
+
[[Category: Large Structures]]
-
[[Category: Bhosle, R C]]
+
[[Category: Almo SC]]
-
[[Category: Bonanno, J B]]
+
[[Category: Bhosle RC]]
-
[[Category: IFN, Atoms-to-Animals:.The Immune Function Network]]
+
[[Category: Bonanno JB]]
-
[[Category: Liu, W]]
+
[[Category: Liu W]]
-
[[Category: Structural genomic]]
+
[[Category: Nathenson SG]]
-
[[Category: Nathenson, S G]]
+
[[Category: Zhan C]]
-
[[Category: Zhan, C]]
+
-
[[Category: Atoms-to-animals: the immune function network]]
+
-
[[Category: Bind tnf receptor hvem and ltbr]]
+
-
[[Category: Cytokine]]
+
-
[[Category: Dcr3]]
+
-
[[Category: Ifn]]
+
-
[[Category: Immune system]]
+
-
[[Category: Jelly-roll fold]]
+
-
[[Category: Light]]
+
-
[[Category: Ltbr]]
+
-
[[Category: Membrane]]
+
-
[[Category: N-glycosylation]]
+
-
[[Category: New hvem]]
+
-
[[Category: Nysgrc]]
+
-
[[Category: PSI, Protein structure initiative]]
+
-
[[Category: Psi-biology]]
+
-
[[Category: Secreted protein]]
+
-
[[Category: Tnf]]
+
-
[[Category: Tnf14]]
+
-
[[Category: Tnfr]]
+

Revision as of 10:55, 24 November 2022

CRYSTAL STRUCTURE OF LIGHT AND DcR3 COMPLEX

PDB ID 4j6g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4j6g"
Personal tools