4j6w

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==Crystal structure of HFQ from Pseudomonas aeruginosa in complex with CTP==
==Crystal structure of HFQ from Pseudomonas aeruginosa in complex with CTP==
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<StructureSection load='4j6w' size='340' side='right' caption='[[4j6w]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='4j6w' size='340' side='right'caption='[[4j6w]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4j6w]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J6W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4j6w]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J6W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u1s|1u1s]], [[1u1t|1u1t]], [[3qui|3qui]], [[4j5y|4j5y]], [[4j6x|4j6x]], [[4j6y|4j6y]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j6w OCA], [https://pdbe.org/4j6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j6w RCSB], [https://www.ebi.ac.uk/pdbsum/4j6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j6w ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hfq, PA4944 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j6w OCA], [http://pdbe.org/4j6w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j6w RCSB], [http://www.ebi.ac.uk/pdbsum/4j6w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j6w ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HFQ_PSEAE HFQ_PSEAE]] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).
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[https://www.uniprot.org/uniprot/HFQ_PSEAE HFQ_PSEAE] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4j6w" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4j6w" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Protein Hfq|Protein Hfq]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pseae]]
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[[Category: Large Structures]]
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[[Category: Lekontseva, N]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Murina, V]]
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[[Category: Lekontseva N]]
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[[Category: Nikulin, A D]]
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[[Category: Murina V]]
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[[Category: Lsm]]
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[[Category: Nikulin AD]]
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[[Category: Mrna]]
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[[Category: Rna binding protein]]
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[[Category: Rna chaperone]]
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[[Category: Srna]]
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Revision as of 10:55, 24 November 2022

Crystal structure of HFQ from Pseudomonas aeruginosa in complex with CTP

PDB ID 4j6w

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