4jd1

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==Crystal Structure of Metallothiol Transferase FosB 2 from Bacillus anthracis str. Ames==
==Crystal Structure of Metallothiol Transferase FosB 2 from Bacillus anthracis str. Ames==
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<StructureSection load='4jd1' size='340' side='right' caption='[[4jd1]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4jd1' size='340' side='right'caption='[[4jd1]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4jd1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis_(strain_ames) Bacillus anthracis (strain ames)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JD1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4jd1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JD1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ir0|4ir0]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jd1 OCA], [https://pdbe.org/4jd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jd1 RCSB], [https://www.ebi.ac.uk/pdbsum/4jd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jd1 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS3818, BA_4109, fosB-2, fosB2, GBAA_4109 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198094 Bacillus anthracis (strain Ames)])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jd1 OCA], [http://pdbe.org/4jd1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jd1 RCSB], [http://www.ebi.ac.uk/pdbsum/4jd1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jd1 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN]] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512]
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[https://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anderson, W F]]
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[[Category: Bacillus anthracis str. Ames]]
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[[Category: Structural genomic]]
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[[Category: Large Structures]]
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[[Category: Hamilton, C J]]
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[[Category: Anderson WF]]
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[[Category: Jedrzejczak, R]]
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[[Category: Hamilton CJ]]
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[[Category: Joachimiak, A]]
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[[Category: Jedrzejczak R]]
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[[Category: Kim, Y]]
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[[Category: Joachimiak A]]
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[[Category: Maltseva, N]]
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[[Category: Kim Y]]
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[[Category: Sharma, S V]]
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[[Category: Maltseva N]]
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[[Category: Alpha/beta fold]]
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[[Category: Sharma SV]]
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[[Category: Csgid]]
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[[Category: Cytosol]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Transferase]]
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Revision as of 11:06, 24 November 2022

Crystal Structure of Metallothiol Transferase FosB 2 from Bacillus anthracis str. Ames

PDB ID 4jd1

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