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4jnx

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==Crystal structure of RNA silencing suppressor p19 complexed with double-helical RNA 20mer pG(CUG)6C==
==Crystal structure of RNA silencing suppressor p19 complexed with double-helical RNA 20mer pG(CUG)6C==
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<StructureSection load='4jnx' size='340' side='right' caption='[[4jnx]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4jnx' size='340' side='right'caption='[[4jnx]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4jnx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Tbsv Tbsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JNX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JNX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4jnx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_bushy_stunt_virus Tomato bushy stunt virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JNX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JNX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4j39|4j39]], [[4e48|4e48]], [[4jgn|4jgn]], [[4jk0|4jk0]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jnx OCA], [https://pdbe.org/4jnx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jnx RCSB], [https://www.ebi.ac.uk/pdbsum/4jnx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jnx ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jnx OCA], [http://pdbe.org/4jnx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jnx RCSB], [http://www.ebi.ac.uk/pdbsum/4jnx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jnx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK]] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
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[https://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
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==See Also==
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*[[P19|P19]]
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*[[RNA silencing suppressor|RNA silencing suppressor]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Tbsv]]
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[[Category: Large Structures]]
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[[Category: Katorcha, E]]
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[[Category: Tomato bushy stunt virus]]
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[[Category: Malinina, L]]
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[[Category: Katorcha E]]
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[[Category: Popov, A N]]
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[[Category: Malinina L]]
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[[Category: Dimer]]
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[[Category: Popov AN]]
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[[Category: Protein-rna complex]]
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[[Category: Rna binding protein-rna complex]]
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[[Category: Rna silencing suppression]]
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[[Category: Trinucleotide repeat]]
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Revision as of 11:26, 24 November 2022

Crystal structure of RNA silencing suppressor p19 complexed with double-helical RNA 20mer pG(CUG)6C

PDB ID 4jnx

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