4jqp

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==X-ray crystal structure of a 4-hydroxythreonine-4-phosphate dehydrogenase from Burkholderia phymatum==
==X-ray crystal structure of a 4-hydroxythreonine-4-phosphate dehydrogenase from Burkholderia phymatum==
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<StructureSection load='4jqp' size='340' side='right' caption='[[4jqp]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<StructureSection load='4jqp' size='340' side='right'caption='[[4jqp]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4jqp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burp8 Burp8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JQP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4jqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paraburkholderia_phymatum_STM815 Paraburkholderia phymatum STM815]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JQP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pdxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391038 BURP8])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jqp OCA], [https://pdbe.org/4jqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jqp RCSB], [https://www.ebi.ac.uk/pdbsum/4jqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jqp ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxythreonine-4-phosphate_dehydrogenase 4-hydroxythreonine-4-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.262 1.1.1.262] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jqp OCA], [http://pdbe.org/4jqp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jqp RCSB], [http://www.ebi.ac.uk/pdbsum/4jqp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jqp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/B2JVC5_BURP8 B2JVC5_BURP8]] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity).[SAAS:SAAS005255_004_027395][HAMAP-Rule:MF_00536]
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[https://www.uniprot.org/uniprot/B2JVC5_PARP8 B2JVC5_PARP8]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 4-hydroxythreonine-4-phosphate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Burp8]]
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[[Category: Paraburkholderia phymatum STM815]]
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[[Category: Structural genomic]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Niaid]]
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[[Category: Oxidoreductase]]
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[[Category: Ssgcid]]
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Revision as of 11:31, 24 November 2022

X-ray crystal structure of a 4-hydroxythreonine-4-phosphate dehydrogenase from Burkholderia phymatum

PDB ID 4jqp

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