Sandbox

The androgen receptor (AR) belongs to the steroid hormone group nuclear receptor family with the estrogen, progesterone, glucocorticoid and mineralcorticoid receptor.

AR mediate the actions of testosterone and a more biologically active form, dihydrotestosterone (DHT), which are the male sex hormones required for development of the male reproductive system and secondary sexual characteristics. This receptor is expressed in a diverse range of tissues, because they have significant biological actions in many systems.

Structure

Function

Structural highlights

3D Structures of androgen receptor