Sandbox Q123
From Proteopedia
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== Relevance == | == Relevance == | ||
| - | FN is associated with inflammation area and the process of wound healing<ref name="Proctor"/><ref name="Mosher"/>. Local treatment of fibronectin has a potential role in accelerating wound closure and the decrease in fibronectin expression can result in poorly healed wound<ref name="Ana">PMID:27554818</ref>. In addition, Fn is considered as a potential marker for radiation resistance. | + | FN is associated with inflammation area and the process of wound healing<ref name="Proctor"/><ref name="Mosher"/>. Local treatment of fibronectin has a potential role in accelerating wound closure and the decrease in fibronectin expression can result in poorly healed wound<ref name="Ana">PMID:27554818</ref>. In addition, Fn is considered as a potential marker for radiation resistance<ref name="Fredrik">PMID:20930522</ref>. |
== Disease == | == Disease == | ||
Revision as of 13:50, 29 November 2022
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References
- ↑ 1.0 1.1 1.2 Pankov R, Yamada KM. Fibronectin at a glance. J Cell Sci. 2002 Oct 15;115(Pt 20):3861-3. PMID:12244123
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Proctor RA. Fibronectin: a brief overview of its structure, function, and physiology. Rev Infect Dis. 1987 Jul-Aug;9 Suppl 4:S317-21. doi:, 10.1093/clinids/9.supplement_4.s317. PMID:3326130 doi:http://dx.doi.org/10.1093/clinids/9.supplement_4.s317
- ↑ Hynes R. Molecular biology of fibronectin. Annu Rev Cell Biol. 1985;1:67-90. doi: 10.1146/annurev.cb.01.110185.000435. PMID:3916323 doi:http://dx.doi.org/10.1146/annurev.cb.01.110185.000435
- ↑ 4.0 4.1 4.2 4.3 Mosher DF. Physiology of fibronectin. Annu Rev Med. 1984;35:561-75. doi: 10.1146/annurev.me.35.020184.003021. PMID:6326663 doi:http://dx.doi.org/10.1146/annurev.me.35.020184.003021
- ↑ Serezani APM, Bozdogan G, Sehra S, Walsh D, Krishnamurthy P, Sierra Potchanant EA, Nalepa G, Goenka S, Turner MJ, Spandau DF, Kaplan MH. IL-4 impairs wound healing potential in the skin by repressing fibronectin expression. J Allergy Clin Immunol. 2017 Jan;139(1):142-151.e5. doi: , 10.1016/j.jaci.2016.07.012. Epub 2016 Aug 20. PMID:27554818 doi:http://dx.doi.org/10.1016/j.jaci.2016.07.012
- ↑ Jerhammar F, Ceder R, Garvin S, Grenman R, Grafstrom RC, Roberg K. Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma. Cancer Biol Ther. 2010 Dec 15;10(12):1244-51. doi: 10.4161/cbt.10.12.13432. Epub , 2010 Dec 15. PMID:20930522 doi:http://dx.doi.org/10.4161/cbt.10.12.13432
- ↑ Han S, Khuri FR, Roman J. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways. Cancer Res. 2006 Jan 1;66(1):315-23. PMID:16397245 doi:http://dx.doi.org/10.1158/0008-5472.CAN-05-2367
