This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4k77
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==JAK1 kinase (JH1 domain) in complex with compound 6== | ==JAK1 kinase (JH1 domain) in complex with compound 6== | ||
| - | <StructureSection load='4k77' size='340' side='right' caption='[[4k77]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='4k77' size='340' side='right'caption='[[4k77]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4k77]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4k77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K77 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1Q4:4-(CYCLOHEXYLAMINO)PYRIDO[3,4-D]PYRIMIDIN-8(7H)-ONE'>1Q4</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1Q4:4-(CYCLOHEXYLAMINO)PYRIDO[3,4-D]PYRIMIDIN-8(7H)-ONE'>1Q4</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k77 OCA], [https://pdbe.org/4k77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k77 RCSB], [https://www.ebi.ac.uk/pdbsum/4k77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k77 ProSAT]</span></td></tr> | |
| - | + | ||
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 21: | Line 18: | ||
</div> | </div> | ||
<div class="pdbe-citations 4k77" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4k77" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Janus kinase 3D structures|Janus kinase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Eigenbrot | + | [[Category: Eigenbrot C]] |
| - | [[Category: Shia | + | [[Category: Shia S]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 11:43, 30 November 2022
JAK1 kinase (JH1 domain) in complex with compound 6
| |||||||||||
