4k90

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==Extracellular metalloproteinase from Aspergillus==
==Extracellular metalloproteinase from Aspergillus==
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<StructureSection load='4k90' size='340' side='right' caption='[[4k90]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='4k90' size='340' side='right'caption='[[4k90]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4k90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspfu Aspfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K90 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4k90]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K90 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=BO3:BORIC+ACID'>BO3</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=BO3:BORIC+ACID'>BO3</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mep, AFUA_8G07080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=330879 ASPFU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k90 OCA], [https://pdbe.org/4k90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k90 RCSB], [https://www.ebi.ac.uk/pdbsum/4k90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k90 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k90 OCA], [http://pdbe.org/4k90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k90 RCSB], [http://www.ebi.ac.uk/pdbsum/4k90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k90 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ELM_ASPFU ELM_ASPFU]] Secreted metalloproteinase that allows assimilation of proteinaceous substrates and probably acts as a virulence factor (By similarity). Catalyzes the hydrolysis of elastin.
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[https://www.uniprot.org/uniprot/ELM_ASPFU ELM_ASPFU] Secreted metalloproteinase that allows assimilation of proteinaceous substrates and probably acts as a virulence factor (By similarity). Catalyzes the hydrolysis of elastin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aspfu]]
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[[Category: Aspergillus fumigatus Af293]]
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[[Category: Fernandez, D]]
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[[Category: Large Structures]]
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[[Category: Monod, M]]
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[[Category: Fernandez D]]
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[[Category: Pallares, I]]
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[[Category: Monod M]]
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[[Category: Russi, S]]
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[[Category: Pallares I]]
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[[Category: Vendrell, J]]
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[[Category: Russi S]]
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[[Category: Hydrolase]]
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[[Category: Vendrell J]]
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[[Category: M36 protease]]
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Revision as of 11:46, 30 November 2022

Extracellular metalloproteinase from Aspergillus

PDB ID 4k90

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