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4kg2

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Current revision (11:56, 30 November 2022) (edit) (undo)
 
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==Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Cefotaxime==
==Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Cefotaxime==
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<StructureSection load='4kg2' size='340' side='right' caption='[[4kg2]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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<StructureSection load='4kg2' size='340' side='right'caption='[[4kg2]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kg2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KG2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kg2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KG2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CEF:CEFOTAXIME,+C3+CLEAVED,+OPEN,+BOUND+FORM'>CEF</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CEF:CEFOTAXIME,+C3+CLEAVED,+OPEN,+BOUND+FORM'>CEF</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jxg|4jxg]], [[4ken|4ken]], [[4kg5|4kg5]], [[4kg6|4kg6]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kg2 OCA], [https://pdbe.org/4kg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kg2 RCSB], [https://www.ebi.ac.uk/pdbsum/4kg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kg2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ampC, ampA, b4150, JW4111 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kg2 OCA], [http://pdbe.org/4kg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/4kg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kg2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI]] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
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[https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ecoli]]
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[[Category: Large Structures]]
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[[Category: Baggett, V L]]
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[[Category: Baggett VL]]
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[[Category: Docter, B E]]
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[[Category: Docter BE]]
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[[Category: Powers, R A]]
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[[Category: Powers RA]]
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[[Category: Wallar, B J]]
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[[Category: Wallar BJ]]
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[[Category: Acyl-enzyme complex]]
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[[Category: Cephalosporinase]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Serine hydrolase]]
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Current revision

Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Cefotaxime

PDB ID 4kg2

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