4kt2

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<StructureSection load='4kt2' size='340' side='right'caption='[[4kt2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4kt2' size='340' side='right'caption='[[4kt2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4kt2]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrsd Chrsd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KT2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4kt2]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens_DSM_3043 Chromohalobacter salexigens DSM 3043]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KT2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KT2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kpl|4kpl]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kt2 OCA], [https://pdbe.org/4kt2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kt2 RCSB], [https://www.ebi.ac.uk/pdbsum/4kt2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kt2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Csal_2974 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=290398 CHRSD])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kt2 OCA], [http://pdbe.org/4kt2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kt2 RCSB], [http://www.ebi.ac.uk/pdbsum/4kt2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kt2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DMGD_CHRSD DMGD_CHRSD] Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chrsd]]
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[[Category: Chromohalobacter salexigens DSM 3043]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mannonate dehydratase]]
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[[Category: Almo SC]]
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[[Category: Almo, S C]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, A A]]
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[[Category: Fedorov EV]]
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[[Category: Fedorov, E V]]
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[[Category: Gerlt JA]]
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[[Category: Gerlt, J A]]
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[[Category: Wichelecki D]]
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[[Category: Wichelecki, D]]
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[[Category: D-mannonate dehydratase]]
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[[Category: Enolase fold]]
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[[Category: Hydrolase]]
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Revision as of 09:12, 7 December 2022

Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with mg and glycerol

PDB ID 4kt2

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