4l5f

<StructureSection load='4l5f' size='340' side='right' caption='[[4l5f]], [[Resolution|resolution]] 2.45&Aring;' scene=''>

<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L5F FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">E ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11053 Dengue virus 1])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [http://pdbe.org/4l5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [http://www.ebi.ac.uk/pdbsum/4l5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l5f ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

*[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]]

[[Category: Edeling, M A]]

[[Category: Fremont, D H]]

[[Category: Nelson, C A]]

[[Category: Virus]]