7t3n

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Current revision (10:01, 14 December 2022) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7t3n is ON HOLD until Paper Publication
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==R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2)==
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<StructureSection load='7t3n' size='340' side='right'caption='[[7t3n]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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Authors: Li, F., Stroud, R.M., Edwards, R.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7t3n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T3N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T3N FirstGlance]. <br>
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Description: R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5B:(1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC+ACID'>C5B</scene>, <scene name='pdbligand=I7Y:(2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl+4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside'>I7Y</scene>, <scene name='pdbligand=P1L:S-PALMITOYL-L-CYSTEINE'>P1L</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t3n OCA], [https://pdbe.org/7t3n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t3n RCSB], [https://www.ebi.ac.uk/pdbsum/7t3n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t3n ProSAT]</span></td></tr>
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[[Category: Stroud, R.M]]
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</table>
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[[Category: Edwards, R.H]]
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== Function ==
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[[Category: Li, F]]
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[https://www.uniprot.org/uniprot/VGLU2_RAT VGLU2_RAT] Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate.<ref>PMID:11502256</ref> <ref>PMID:11551935</ref> <ref>PMID:11698619</ref> <ref>PMID:11698620</ref> <ref>PMID:17046815</ref> <ref>PMID:18080752</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Rattus norvegicus]]
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[[Category: Edwards RH]]
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[[Category: Li F]]
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[[Category: Stroud RM]]

Current revision

R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2)

PDB ID 7t3n

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