2g3v

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<StructureSection load='2g3v' size='340' side='right'caption='[[2g3v]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2g3v' size='340' side='right'caption='[[2g3v]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2g3v]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2g3v]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3V FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cagS, cag13, HP0534 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 ATCC 43504])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3v OCA], [https://pdbe.org/2g3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3v RCSB], [https://www.ebi.ac.uk/pdbsum/2g3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3v ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3v OCA], [https://pdbe.org/2g3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3v RCSB], [https://www.ebi.ac.uk/pdbsum/2g3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3v ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/CAGS_HELPY CAGS_HELPY]
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CagZ, a 23 kDa protein encoded by the cagZ gene (HP0526) of the cag pathogenicity island of Helicobacter pylori, has been cloned, over-expressed, purified and its three-dimensional structure determined. The protein consists of a single compact L-shaped domain, composed of seven alpha-helices including about 70% of the total residues. Three-dimensional homology searches did not reveal structural homologues, and CagZ can be considered representative of a new protein fold. The presence of a disordered C-terminal tail and the nature of the molecular surface suggest that CagZ may participate in the interaction of effector proteins with one or more components of the H.pylori type IV secretion system on the cytoplasmic side of the inner membrane.
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Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system.,Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G J Mol Biol. 2004 Jul 16;340(4):881-9. PMID:15223328<ref>PMID:15223328</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2g3v" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43504]]
 
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[[Category: Large Structures]]
 
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[[Category: Angelini, A]]
 
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[[Category: Battistutta, R]]
 
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[[Category: Cendron, L]]
 
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[[Category: Montecucco, C]]
 
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[[Category: Seydel, A]]
 
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[[Category: Tasca, E]]
 
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[[Category: Zanotti, G]]
 
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Pathogenicity island]]
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[[Category: Large Structures]]
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[[Category: Type iv secretion system]]
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[[Category: Angelini A]]
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[[Category: Unknown function]]
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[[Category: Battistutta R]]
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[[Category: Cendron L]]
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[[Category: Montecucco C]]
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[[Category: Seydel A]]
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[[Category: Tasca E]]
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[[Category: Zanotti G]]

Revision as of 10:38, 14 December 2022

Crystal structure of CagS (HP0534, Cag13) from Helicobacter pylori

PDB ID 2g3v

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