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4lcj

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==CtBP2 in complex with substrate MTOB==
==CtBP2 in complex with substrate MTOB==
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<StructureSection load='4lcj' size='340' side='right' caption='[[4lcj]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
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<StructureSection load='4lcj' size='340' side='right'caption='[[4lcj]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lcj]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LCJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lcj]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LCJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KMT:4-(METHYLSULFANYL)-2-OXOBUTANOIC+ACID'>KMT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KMT:4-(METHYLSULFANYL)-2-OXOBUTANOIC+ACID'>KMT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lce|4lce]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lcj OCA], [https://pdbe.org/4lcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lcj RCSB], [https://www.ebi.ac.uk/pdbsum/4lcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lcj ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTBP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lcj OCA], [http://pdbe.org/4lcj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lcj RCSB], [http://www.ebi.ac.uk/pdbsum/4lcj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lcj ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN]] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.
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[https://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Hilbert, B J]]
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[[Category: Large Structures]]
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[[Category: Royer, W E]]
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[[Category: Hilbert BJ]]
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[[Category: Schiffer, C A]]
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[[Category: Royer Jr WE]]
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[[Category: D-isomer 2-hydroxyacid dehydrogenase]]
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[[Category: Schiffer CA]]
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[[Category: Oxidoreductase-oxidoreductase substrate complex]]
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[[Category: Rossmann fold]]
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[[Category: Transcriptional corepressor]]
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Revision as of 10:51, 14 December 2022

CtBP2 in complex with substrate MTOB

PDB ID 4lcj

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