4lij

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==Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution==
==Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution==
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<StructureSection load='4lij' size='340' side='right' caption='[[4lij]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='4lij' size='340' side='right'caption='[[4lij]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lij]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LIJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lij]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LIJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lij OCA], [https://pdbe.org/4lij PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lij RCSB], [https://www.ebi.ac.uk/pdbsum/4lij PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lij ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BC017247, FUBP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lij OCA], [http://pdbe.org/4lij PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lij RCSB], [http://www.ebi.ac.uk/pdbsum/4lij PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lij ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FUBP1_HUMAN FUBP1_HUMAN]] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.<ref>PMID:8125259</ref>
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[https://www.uniprot.org/uniprot/FUBP1_HUMAN FUBP1_HUMAN] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.<ref>PMID:8125259</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Biology, Partnership for T-Cell]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Partnership for T-Cell Biology]]
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[[Category: TCELL, Partnership for T-Cell Biology]]
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[[Category: Jcsg]]
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[[Category: Kh domain]]
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[[Category: Partnership for t-cell biology]]
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[[Category: Pf00013]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Rna binding protein]]
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[[Category: Rna-binding protein]]
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[[Category: Tcell]]
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Revision as of 11:03, 14 December 2022

Crystal structure of a far upstream element (FUSE) binding protein 1 (FUBP1) from Homo sapiens at 1.95 A resolution

PDB ID 4lij

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